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Qiong DAI MD, Bei LIU MD, Yukai DU MM,
《医学前沿(英文)》 2009年 第3卷 第4期 页码 452-458 doi: 10.1007/s11684-009-0080-z
关键词: meta-analysis breast cancer risk factors reproductive factors oral contraceptive use
《医学前沿(英文)》 2022年 第16卷 第6期 页码 827-858 doi: 10.1007/s11684-022-0948-8
关键词: infertility stem cell therapy mesenchymal stem cells pluripotent stem cells
Mengmeng ZHAO,Juanjuan QIAN,Jiexiong XIE,Tiantian CUI,Songling FENG,Guoqiang WANG,Ruining WANG,Guihong ZHANG
《农业科学与工程前沿(英文)》 2016年 第3卷 第2期 页码 153-160 doi: 10.15302/J-FASE-2016097
张君娴,杨婷,徐晓帆,龙春燕,刘建苏,李莉
《中国工程科学》 2015年 第17卷 第6期 页码 57-60
了解乌鲁木齐市流动育龄妇女的避孕状况,为今后开展避孕方法知情选择优质服务提供参考。采用分层-整群-随机抽样的方法,对18~50岁符合条件的对象进行问卷调查,主要包括人口学特征、避孕措施的使用情况等。采用卡方检验和多因素Logistic回归方法进行统计分析。本次调查的106 568例流动育龄妇女中,避孕方法使用比例为92.78 %,避孕方法的选择依次为宫内节育器(65.74 %)、药物(23.17 %,包括口服避孕药、皮下埋植剂、避孕针等含药避孕方法)、避孕套(9.06 %)、绝育术(2.03 %)。多因素Logistic回归分析显示民族、学历、职业、婚姻状况和性生活频率对避孕方法的使用有影响。应根据不同民族的情况和流动育龄妇女的人口学特征,提供有针对性和个性化的避孕方法知情选择指导和服务。
A brief review of microRNA and its role in PRRSV infection and replication
Xuekun GUO,Wenhai FENG
《农业科学与工程前沿(英文)》 2014年 第1卷 第2期 页码 114-120 doi: 10.15302/J-FASE-2014022
关键词: porcine reproductive and respiratory syndrome virus (PRRSV) microRNA antiviral viral tropism
Risk factors of prognosis after acute kidney injury in hospitalized patients
null
《医学前沿(英文)》 2017年 第11卷 第3期 页码 393-402 doi: 10.1007/s11684-017-0532-9
The risk factors, especially laboratory indicators, of prognosis after acute kidney injury (AKI) remain unclear. We conducted a retrospective survey of Chinese People’s Liberation Army General Hospital from January 1, 2012 to December 31, 2012 according to the AKI diagnosis standard issued by Kidney Disease Improving Global Outcomes. The epidemiological features and factors influencing hospital mortality and renal function recovery were evaluated through logistic regression analysis. Among 77 662 cases of hospitalized patients, 1387 suffered from AKI. The incidence rate and mortality of AKI were 1.79% and 14.56%, respectively. Multivariate logistic regression analysis revealed that high AKI stage, age greater than 80 years, neoplastic disease, low cardiac output, increased white blood cell count, and decreased platelet count and serum albumin levels were the risk factors affecting the mortality of AKI patients. Conversely, body mass index between 28 and 34.9 was a protective factor. Increased AKI stage, tumor disease, post-cardiopulmonary resuscitation, and RRT were the risk factors of renal function recovery upon discharge. In addition to traditional risk factors, white blood cell count, platelet count, albumin, and BMI were the predictors of the mortality of AKI patients. No laboratory indicators were found to be the risk factors of renal function recovery in AKI patients.
张君娴,周彦岭,刘建苏,王珊,李莉,梅桂,李琳,巴哈古丽·塔吉曼提
《中国工程科学》 2014年 第16卷 第5期 页码 85-89
了解乌鲁木齐市流动人口育龄妇女阴道炎感染患病现况,为今后的生殖道感染防治提供参考依据。本文采取分层-整群-抽样的方法,在乌鲁木齐市六区一县流动人口较集中的社区,由经过培训的医生对18~50 岁的流动育龄妇女进行生殖道感染问卷调查、妇科检查与实验室检查。本研究共检查106 568 名符合条件的流动妇女,其中细菌性阴道炎的患病率为16.15 %;滴虫性阴道炎的患病率为12.66 %;霉菌性阴道炎的患病率为4.52 %。3 种阴道炎的患病率为19.84 %。应根据不同民族的特点,采取一定的防治措施,降低流动育龄妇女的阴道炎患病率,特别是对文化程度为文盲或小学、职业为农民、月收入在1 500~1 599 元的对象,应加大干预的力度。
Jie HOU,Rui LI,Hongfang MA,Songlin QIAO,Gaiping ZHANG
《农业科学与工程前沿(英文)》 2016年 第3卷 第1期 页码 65-71 doi: 10.15302/J-FASE-2016086
关键词: PRRSV porcine sialoadhesin V-set Ig-like domain Drosophila S2 cell crystallization
Reproductive toxicity study with a novel deoxyguanosine analogue (Metacavir) in pregnant SD rats
null
《医学前沿(英文)》 2015年 第9卷 第1期 页码 82-89 doi: 10.1007/s11684-015-0376-0
Our preliminary studies demonstrated that Metacavir has potential to become a new anti-HBV agent. The main targets of the toxic effects of Metacavir, in rhesus monkeys, were gastrointestinal tracts, liver, blood, and kidneys, which were not related to mitochondrial effects. In this study, the maternal toxicity, embryo-fetal developmental toxicity and teratogenicity were studied in pregnant Sprague-Dawley rats after intragastric administration of Metacavir (200, 100, 50, 0 mg/kg body weight) during the first 6–15 days of pregnancy. Slower weight gain was observed in 5 out of 21 rats subjected to a 200 mg/kg dose, as well as 2 out of 20 subjected to a 100 mg/kg dose. Compared with the solvent control group, the calibration weight gain in the 200 mg/kg and 100 mg/kg dosage groups respectively, during first 6–20 pregnant days were significantly different (P<0.01, P<0.05). Significant dose related adverse effects to other reproductive parameters were not seen in F0 and F1, but the number of stillbirths in high dose group showed notably difference compared with the control group (P<0.05), while the litter incidence showed no difference. No Metacavir-associated pathological changes were observed. The present research indicated that at a dose of 200 mg/(kg·d) (i.e., 40 times the effective dose in rats), Metacavir shows some maternal toxicity to SD rats. The embryotoxicity in the 200 mg/kg group encompass decreased fetal body weight, and higher fetal mortality rates, compared with the control group. However, the litter incidence showed no statistical difference. All the treated rats displayed normal bone development, no teratogenicity and without adverse effects on fetal development, thus indicating that below a dose of 200 mg/(kg·d) there is no teratogenic side effects.
关键词: deoxyguanosine analogue Metacavir pregnancy maternal toxicity embryo toxicity teratogenicity
Factors affecting the distribution of microplastics in soils of China
《环境科学与工程前沿(英文)》 2023年 第17卷 第9期 doi: 10.1007/s11783-023-1710-4
● Microplastic (MP) abundance in soil of China was highly heterogeneous.
关键词: Microplastic distribution Microplastic heterogeneity Effecting factors Agriculture Socio-economic factors
Epidemic obesity in children and adolescents: risk factors and prevention
Eun Young Lee, Kun-Ho Yoon
《医学前沿(英文)》 2018年 第12卷 第6期 页码 658-666 doi: 10.1007/s11684-018-0640-1
关键词: obesity children adolescents epidemiology risk factor prevention
《农业科学与工程前沿(英文)》 2023年 第10卷 第4期 页码 541-552 doi: 10.15302/J-FASE-2023518
Agricultural non-point source pollution is increasingly an important issue affecting surface water quality. Currently, the majority of the studies on nitrogen loss have focused on the agricultural field scale, however, the response of surface water quality at the watershed scale into the nitrogen loss at the field scale is poorly understood. The present study systematically reviewed the critical processes and major factors that nitrogen transport from farm fields to surface water bodies. The critical processes of farmland nitrogen entering surface water bodies involve the processes of nitrogen transport from farmland to ditches and the transformation processes of nitrogen during migration in ditches/rivers. Nitrogen transport from farmland to ditches is one of the prerequisites and critical processes for farmland nitrogen transport to surface water bodies. The transformation of nitrogen forms in ditches/rivers is an intermediate process in the migration of nitrogen from farmland to surface water bodies. Nitrogen loss from farmland is related to soil storage and exogenous inputs. Therefore, nitrogen input management should not only consider the current input, but also the contribution of soil storage due to the historical surpluses. Ditches/rivers have a strong retention capacity for nitrogen, which will significantly affect the process of farmland nitrogen entering surface water bodies. The factors affecting nitrogen transformation in river/ditches can be placed in four categories: (1) factors affecting hydraulic retention time, (2) factors affecting contact area, (3) factors affecting biological activity, and (4) forms and amount of nitrogen loading to river/ditches. Ditch systems are more biologically (including plants and microbes) active than rivers with biological factors having a greater influence on nitrogen transformation. When developing pollution prevention and control strategies, ecological ditches can be constructed to increase biological activity and reduce the amount of surplus nitrogen entering the water body. The present research should be valuable for the evaluation of environment impacts of nitrogen loss and the non-point source pollution control.
关键词: nitrogen loss from soil transformation farm field scale watershed scale
Fengxia YIN,Hui LIU,Shorgan BOU,Guangpeng LI
《农业科学与工程前沿(英文)》 2014年 第1卷 第2期 页码 104-113 doi: 10.15302/J-FASE-2014003
关键词: nuclear reprogramming somatic cell transcription factors transcriptomics
Guangbo HAO,Haiyang LI,Suzen KEMALCAN,Guimin CHEN,Jingjun YU
《机械工程前沿(英文)》 2016年 第11卷 第2期 页码 129-134 doi: 10.1007/s11465-016-0392-z
In order to accurately model compliant mechanism utilizing plate flexures, qualitative planar stress (Young’s modulus) and planar strain (plate modulus) assumptions are not feasible. This paper investigates a quantitative equivalent modulus using nonlinear finite element analysis (FEA) to reflect coupled factors in affecting the modelling accuracy of two typical distributed-compliance mechanisms. It has been shown that all parameters have influences on the equivalent modulus with different degrees; that the presence of large load-stiffening effect makes the equivalent modulus significantly deviate from the planar assumptions in two ideal scenarios; and that a plate modulus assumption is more reasonable for a very large out-of-plane thickness if the beam length is large.
关键词: coupling factors modelling accuracy compliant mechanisms equivalent modulus
Qi LI, Jinxi SONG, Anlei WEI, Bo ZHANG
《环境科学与工程前沿(英文)》 2013年 第7卷 第6期 页码 875-885 doi: 10.1007/s11783-013-0568-2
关键词: influencing factors ecosystem health ecological and environmental functions the Weihe River Shaanxi Province
标题 作者 时间 类型 操作
Meta-analysis of the risk factors of breast cancer concerning reproductive factors and oral contraceptive
Qiong DAI MD, Bei LIU MD, Yukai DU MM,
期刊论文
Cell therapy for the treatment of reproductive diseases and infertility: an overview from the mechanism
期刊论文
Characterization of polyclonal antibodies against nonstructural protein 9 from the porcine reproductive
Mengmeng ZHAO,Juanjuan QIAN,Jiexiong XIE,Tiantian CUI,Songling FENG,Guoqiang WANG,Ruining WANG,Guihong ZHANG
期刊论文
A brief review of microRNA and its role in PRRSV infection and replication
Xuekun GUO,Wenhai FENG
期刊论文
Structural prediction of porcine sialoadhesin V-set Ig-like domain sheds some light on its role in porcine reproductive
Jie HOU,Rui LI,Hongfang MA,Songlin QIAO,Gaiping ZHANG
期刊论文
Reproductive toxicity study with a novel deoxyguanosine analogue (Metacavir) in pregnant SD rats
null
期刊论文
Epidemic obesity in children and adolescents: risk factors and prevention
Eun Young Lee, Kun-Ho Yoon
期刊论文
CRITICAL PROCESSES AND MAJOR FACTORS THAT DRIVE NITROGEN TRANSPORT FROM FARMLAND TO SURFACE WATER BODIES
期刊论文
Oocyte-associated transcription factors in reprogramming after somatic cell nuclear transfer: a review
Fengxia YIN,Hui LIU,Shorgan BOU,Guangpeng LI
期刊论文
Understanding coupled factors that affect the modelling accuracy of typical planar compliant mechanisms
Guangbo HAO,Haiyang LI,Suzen KEMALCAN,Guimin CHEN,Jingjun YU
期刊论文